Therapeutics · Vaccines

Strategy for
Biopharma.

We work with both large and small companies in therapeutics and vaccines. We focus on strategy projects from R&D across the product development lifecycle, to commercial, market access, supply chain, and corporate development. Our projects span the asset/product, portfolio, and firm levels.

FEATURED PERSPECTIVE

  • Biopharma , 
  • Payers , 
  • Institutional

Outcomes Based Arrangements in Biopharma

Today’s advanced therapies target devastating diseases with high unmet need. Given the urgent medical need (and pressure from patient advocates), regulators increasingly must make decisions based on early, incomplete data when it comes to durability, real-world effectiveness, and cost-effectiveness – all while bearing costs that can exceed $1 million per patient.

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"In today’s environment, manufacturers may be less likely to enter into these arrangements"

— Recon analysis

Emerging blood-brain barrier drugs in development

  • Biopharma
Despite the historical difficulty in designing therapeutics that cross the BBB, Denali’s landmark approval could signal an inflection point for the BBB-crossing therapeutic pipeline.

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Outcomes Based Arrangements in Biopharma

  • Biopharma , 
  • Payers , 
  • Institutional
Today’s advanced therapies target devastating diseases with high unmet need. Given the urgent medical need (and pressure from patient advocates), regulators increasingly must make decisions based on early, incomplete data when it comes to durability, real-world effectiveness, and cost-effectiveness – all while bearing costs that can exceed $1 million per patient.

Read more

Winning on route of administration isn’t enough – lessons from Sotyktu

  • Biopharma
Introduction As we described in a prior whitepaper, explaining over- a…

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SELECTED CASE STUDIES

How we've helped our biopharma clients

Representative engagements, anonymized. Each pairs deep sector knowledge with rigorous, structured analysis.

CDMO modality investment strategy

A contract manufacturer needed a full strategy refresh for the decade ahead: markets to serve, capabilities to build, and the cost to get there.

Contract manufacturing service prioritization

Gene therapy disease assessment

A gene therapy biotech with a novel approach to a fast-moving disease area needed an objective read on the opportunity and on whether it had a credible path to win there.

Crowded market entry decision

Decentralized clinical trial product strategy

A large pharma health-tech arm needed to understand why its decentralized-trial tools weren't landing with users and how to find a defensible point of differentiation.

Clinical research product roadmap